Zapenia is prescribed for:
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Clozapine belongs to the atypical antipsychotic class and has a unique receptor binding profile. It interacts with dopamine receptors (D1, D2, D3, D5) but shows higher selectivity for D4 receptors, which may explain its reduced risk of extrapyramidal side effects. It also blocks adrenergic, cholinergic, histaminergic, and serotonergic receptors, contributing to its broad pharmacologic action.
For Schizophrenia (Adults 16+):
Gradually increase by 25–50 mg/day (maximum 25 mg/day in the elderly) over 2–3 weeks up to 300 mg/day in divided doses (larger dose at night).
For Parkinson’s Disease Psychosis:
In rare cases, the dose can be increased weekly to a maximum of 100 mg/day.
Use only as directed by a registered physician.
Symptoms include:
Management:
Common: Drowsiness, dizziness, constipation, hypersalivation, headache, nausea, weight gain
Less common: Heartburn, dry mouth, abdominal discomfort
Store below 30°C. Keep away from light and out of children's reach.
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